March 9, 2017 | Thornton Law Firm Contact the Boston law firm of Thornton Law Firm LLP online or call us toll-free 1-888-341-1405 for a free consultation with a recognized leader in Massachusetts drug and medical device litigation. WHAT IS INVOKANA? Invokana is a sodium-glucose transporter-2 (SGLT2) inhibitor used to treat Type 2 diabetes. SGLT2s are a new category of diabetes drugs introduced in 2013. Other SGLT inhibitors on the market include: Brand Name Active Ingredients Manufacturer Invokana Canagliflozin Johnson & Johnson Invokamet Canagliflozin & Metformin Johnson & Johnson Farxiga Dapagliflozin AstraZenica XigduoXR Dapagliflozin & Metformin extended release AstraZenica Jardiance Empagliflozin Lilly & Boehringer-Ingelheim Glyxambi Empagliflozin & Linagliptin Lilly & Boehringer-Ingelheim WHY IS IT PRESCRIBED, AND HOW DOES IT WORK? Invokana is a once-daily pill that works to lower blood sugar in patients with Type 2 diabetes. Invokana and other SGLT2s triggers the kidneys to release blood glucose into the urine, thereby lowering blood sugar levels. INVOKANA AND KETOACIDOSIS The FDA issued warnings in May of 2015 that Invokana and other SGLT2s may lead to ketoacidosis. Ketoacidosis is a condition where too much acid (ketones) is produced in the blood. Warning symptoms of ketoacidosis include nausea, difficulty breathing, vomiting, confusion, abdominal pain and unusual fatigue or sleepiness. Ketoacidosis can lead to diabetic coma requiring extensive hospitalization, and even death. INVOKANA AND RISK OF BONE FRACTURES On September 10, 2015 the FDA required manufacturers to add warnings to the Invokana and Invokamet (canagliflozin) labels about: An increased risk of bone fracture, occurring as early as 12 weeks after treatment initiation, observed in patients using canagliflozin. Canagliflozin has also been linked to decreases in bone mineral density at the hip and lumbar spine. The FDA continues to evaluate the other SGLT2 inhibitor class drugs (including dapagliflozin (Farxiga, Xigduo XR) and empagliflozin (Jardiance, Glyxambi, Synjardy) for increased risk of bone fractures. WHAT CAN YOU DO? If you or someone you love has taken Invokana or any other SGLT2 drug and suffered ketoacidosis, or bone fractures or decreased bone density, you may have a legal claim for damages against the manufacturer. Call our Massachusetts Invokana lawyers toll free at 1-888-341-1405, or tell us your story using our online contact form. TRUST OUR MASSACHUSETTS INVOKANA LAWYERS TO HELP Contact the Boston law firm of Thornton Law Firm LLP online or at 1-888-341-1405 for a free consultation with a recognized leader in Massachusetts drug and medical device litigation. You have nothing to risk. We offer a fair and accurate assessment of your case.