What Is Testosterone Replacement Therapy (LowT)?

You’ve seen the ads on TV. Millions of men have been prescribed testosterone replacement therapy  to counteract the routine effects of aging in men (often abbreviated as “LowT”). (The FDA now says it should only be prescribed for extremely low testosterone levels caused by specific medical conditions.) Testosterone replacement therapy can take the form of injections, pills, patches, or gels.  Giving a man added testosterone is said to increase energy, sexual libido, and muscle mass. But the TV commercials didn’t tell you that testosterone use is also associated with several serious medical conditions, including strokes, blood clots, heart attacks, and death.

What Is Testosterone?

Testosterone is a hormone, the sex hormone that makes men men (although women also have testosterone in low levels). It is primarily produced in the testicles. According to the Mayo Clinic, testosterone helps maintain men’s

  • Bone density
  • Fat distribution
  • Muscle strength and mass
  • Facial and body hair
  • Red blood cell production
  • Sex drive
  • Sperm production

What Are the Testosterone Replacement Therapy Drugs?

Type of Drug Product Manufacturer
Gels/On the skin Androgel AbbVie, Inc.
Gels/On the skin Axiron Eli Lilly & Co.
Gels/On the skin Bio-T-Gel BioSante Pharmaceuticals, Inc.
Gels/On the skin First-Testosterone Curis, Inc.
Gels/On the skin Fortesta Endo Pharmaceuticals, Inc.
Gels/On the skin Natesto Endo Pharmaceuticals, Inc.
Gels/On the skin Striant Columbia Laboratories, Inc.
Gels/On the skin Testim Auxilium Pharmaceuticals, Inc.
Gels/On the skin Vogelxo Upsher-Smith Pharmaceuticals, Inc.
Injections Aveed AbbVie, Inc.
Injections Delatestryl Endo Pharmaceuticals, Inc.
Injections Depa-Testadiol Pfizer, Inc.
Injections Depo-Testosterone Pfizer, Inc.
Injections Ditate-DS Savage Laboratories Inc.
Injections Testopel Endo Pharmaceuticals, Inc.
Patches Androderm Actavis, Inc.
Patches Testoderm Alza Corporation
Pills Android ICN Pharmaceuticals, Inc. (now Valeant Pharmaceuticals Int’l)
Pills Metandren Novartis
Pills Methitest Global Pharmaceuticals, div. of Impax Laboratories, Inc.
Pills Oreton Schering
Pills Testred Methyltestosterone ICN Pharmaceuticals, Inc. (now Valeant Pharmaceuticals Int’l)
Pills Virilon Star Pharmaceuticals, Inc.

What Are Testosterone’s Side Effects?

In March of 2015 the FDA issued guidance requiring manufacturers to update product labels “to reflect the possible increased risk of heart attacks and strokes associated with testosterone use.” The agency also instructed medical professionals not to prescribe testosterone for normal conditions of aging. Instead doctors are required to prescribe testosterone only “only for men who have low testosterone levels due to disorders of the testicles, pituitary gland, or brain that cause a condition called hypogonadism.”

In June 2014 the FDA required testosterone product manufacturers include a general warning on the product label to alert doctors and patients of the risk of blood clots in the veins. These blood clots in the veins, also known as venous thromboembolism (VTE), include deep vein thrombosis (DVT) and pulmonary embolism (PE), are venous blood clots not associated with an increase in red blood cells. These blood clots may break off and travel to the heart, lungs or brain where they may cause severe damage.

What Can I Do If I Suffered Side Effects While on Testosterone Replacement Therapy?

If you or someone you love had a stroke, heart attack, or blood clot injuries like deep vein thrombosis and pulmonary embolism while using prescription testosterone replacement products, you may be able to file a testosterone replacement therapy lawsuit. For a free, no-obligation consultation, call our toll-free number 1-888-341-1405 to discuss your case with one of our testosterone replacement therapy lawyers. You can tell us your story using our online contact form as well. You should be aware that all legal claims are subject to short time limits called statutes of limitations. Do not delay seeking legal advice if you believe you have a testosterone replacement therapy claim.