March 9, 2017 | dev Dostinex Quick Reference Guide Generic name Cabergoline Date approved December 23, 1996 Manufacturer Pfizer, Inc. Status On the market New study 1/3/07 Approved use in U.S. Hyperprolactinemia Approved use in Europe Parkinson’s disease Serious side effects Heart valve disease Leaky valves Heart damage Cardiac valvulopathy Heart valve damage Permax Quick Reference Guide Generic name Pergolide Date approved October 6, 1999 Manufacturer Eli Lilly Status Removed 3/29/07 Approved use Parkinson’s disease Serious side effects Heart valve disease Leaky valves Heart damage Cardiac valvulopathy Heart valve damage What are Dostinex and Permax? Dostinex (cabergoline) is manufactured by Pfizer. Permax (pergolide) is manufactured by Eli Lilly. Both are dopamine agonists. Who takes them, and for what conditions? People suffering from Parkinson’s Disease, restless leg syndrome, or hyperprolactinemia, a hormonal disorder, take Dostinex or Permax. How do Dostinex and Permax work? Parkinson’s symptoms appear when cells in the brain stop producing dopamine, a neurotransmitter that influences thought and movement areas of the brain. Dopamine agonists directly stimulate the parts of the brain where dopamine works and mimic its function. Dostinex and Permax have been found in several studies to damage heart valves, causing them to leak. What can you do? If you or someone you love took Dostinex or Permax and suffered from heart valve damage or other serious side effects, you have valuable legal rights. Please call our toll-free number (1-888-341-1395) to discuss your case with one of our Dostinex or Permax injury lawyers. Trust our Massachusetts Dostinex & Permax injury attorneys to help Contact the Boston law firm of Thornton Law Firm LLP online or at 1-888-341-1395 for a free consultation with a recognized leader in Massachusetts drug and medical device litigation. You have nothing to risk. We offer a fair and accurate assessment of your case, and, perhaps, some hope.