Dostinex Quick Reference Guide

Generic name
  • Cabergoline
Date approved
  • December 23, 1996
Manufacturer
  • Pfizer, Inc.
Status
  • On the market
  • New study 1/3/07
Approved use in U.S.
  • Hyperprolactinemia
Approved use in Europe
  • Parkinson’s disease
Serious side effects
  • Heart valve disease
  • Leaky valves
  • Heart damage
  • Cardiac valvulopathy
  • Heart valve damage

Permax Quick Reference Guide

Generic name
  • Pergolide
Date approved
  • October 6, 1999
Manufacturer
  • Eli Lilly
Status
  • Removed 3/29/07
Approved use
  • Parkinson’s disease
Serious side effects
  • Heart valve disease
  • Leaky valves
  • Heart damage
  • Cardiac valvulopathy
  • Heart valve damage

What are Dostinex and Permax?

Dostinex (cabergoline) is manufactured by Pfizer. Permax (pergolide) is manufactured by Eli Lilly. Both are dopamine agonists.

Who takes them, and for what conditions?

People suffering from Parkinson’s Disease, restless leg syndrome, or hyperprolactinemia, a hormonal disorder, take Dostinex or Permax.

How do Dostinex and Permax work?

Parkinson’s symptoms appear when cells in the brain stop producing dopamine, a neurotransmitter that influences thought and movement areas of the brain. Dopamine agonists directly stimulate the parts of the brain where dopamine works and mimic its function.

Dostinex and Permax have been found in several studies to damage heart valves, causing them to leak.

What can you do?

If you or someone you love took Dostinex or Permax and suffered from heart valve damage or other serious side effects, you have valuable legal rights. Please call our toll-free number (1-888-341-1405) to discuss your case with one of our Dostinex or Permax injury lawyers.

Trust our Massachusetts Dostinex & Permax injury attorneys to help

Contact the Boston law firm of Thornton Law Firm LLP online or at 1-888-341-1405 for a free consultation with a recognized leader in Massachusetts drug and medical device litigation. You have nothing to risk. We offer a fair and accurate assessment of your case, and, perhaps, some hope.